Newly Invented Robotic Pills Can End Insulin Injections

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Newly Invented Robotic Pills Can End Insulin Injections

MIT breakthrough: Medication potentially may replace insulin injection

These robotic pills, introduced as the RoboCap, are covered in gelatin, possess a reservoir that is tiny at one end, and have tunneling characteristics within their primary body.

These capsules have a robotic ability to pass through the body’s mucus barrier and small intestines before releasing the medicine ingredients.

The mucus barrier in the intestines that are digestively impenetrable to protein medications before the development of those robotic pills, thus doctors were forced to make do by injecting the medication right into their patients.

Giovanni Traverso, a gastroenterologist at Brigham and Women’s Hospital and Development Assistant Professor of Mechanical Engineering at MIT, stated that,

“By displacing the mucus, we can maximize the dispersion associated with the drug within an area that is regional enhances the absorption of both little molecules and macromolecules.”

Orally administered protein medications begin to degrade also if they find a way to penetrate further, the intestinal tract’s acidic environment breaks down the pharmaceuticals before they cross the mucus barrier.

Nevertheless, these new robotic pills can carry both insulin and vancomycin while effortlessly passing through the mucus digestive tract.

The study’s lead writer, Shriya Srinivasan, essentially built a protective capsule. This supplement is made to readily pass through the tunnel and barrier through mucus.

She described the concept behind the robot pills:

I concluded that we could apply the drug directly to the epithelium if we could get through the mucus. The concept is that after ingesting this capsule, the outer layer will dissolve inside the digestive tract, exposing all of the features that will begin to churn through and clear the mucus.

These gelatin-coated capsules understood as RoboCaps, have a reservoir that is small one end and tunneling characteristics through the majority of this capsule.

These capsules have a motor that begins spinning if they come into touch with a certain PH degree, allowing the capsule to pass past mucus.

The RoboCup temporarily removes any mucus that is present before enhancing local medication to improve absorption.

We can maximize our power to produce the environment that is ideal for the medicine to be absorbed by combining all of these components, according to Traverso.

Pakistan declines India’s ‘Frivolous Accusations’ of Terrorism

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Pakistan declines India's 'Frivolous Accusations' of Terrorism

Foreign Office dismisses Indian accusations as baseless and frivolous.

During a press conference in Vienna, Indian External Affairs Minister Subrahmanyam Jaishankar made a veiled allusion to the fact that the effects of cross-border terrorism cannot be contained to a single geographic area.

Particularly when they are intricately linked to the trafficking of illegal drugs and weapons and other types of international crime.

Without mentioning Pakistan, Jasishankar said,

“Since the epicentre (of terrorism) is so near to India, our experiences and insights are inherently helpful to others.”

In response to questions from the media regarding the Indian minister’s statement, the FO spokesperson insisted that,

India has been in a malicious campaign for the past few years to deceive the international community by spreading “vile anti-Pakistan propaganda” and a “fictitious narrative of victimhood.” This practice ought to end.

The Spokesperson stated

Despite India’s persistent anti-Pakistan rhetoric, the country’s open support for terrorism on Pakistani soil and the existence of state-sponsored terrorism in Indian Illegally Occupied Jammu and Kashmir (IIOJK) cannot be hidden.

Instead of blaming others, the FO officer counselled India to stop its baseless and frivolous accusations against Pakistan.

The spokesperson claimed that a few weeks ago, a dossier with concrete proof of India’s complicity in the 2021 terrorist assault in a quiet Lahore neighbourhood was made public.

“The evidence of Indian involvement in terrorism and sabotage spans decades and geographical areas, from the 2007 Samjhota Express incident, which resulted in the deaths of more than 40 Pakistani nationals on Indian land, to the 2016 arrest of Kulbhushan Jadhav, a serving Indian Navy Commander, from inside Pakistan.”

By highlighting the “saffron terror” of the Rashtriya Swayamsevak Sangh (RSS), a group of Hindu supremacist paramilitary volunteers who have influenced Prime Minister Narendra Modi and helped shape his political ideology, Foreign Minister Bilawal Bhutto Zardari earlier delivered a scathing rebuttal to India’s renewed call for terrorism against Pakistan.

When he served as the state’s chief minister in 2002, Modi earned the nickname “Butcher of Gujarat,” and Bilawal used it to describe him.

India was upset by Bilawal’s criticism of Modi, which prompted the Bharatiya Janata Party, the country’s ruling party, to call for a national protest (BJP).

“I would like to remind the Indian Minister of External Affairs that although Osama Bin Laden is no longer alive, the Butcher of Gujarat is still in power in India. After India’s foreign minister S. Jaishankar accused Pakistan of being the “epicentre of terrorism” for “harbouring Osama bin Laden,” Bilawal claimed that he had been barred from entering the nation until he was elected prime minister.

US Supports Pakistan’s Right To Defend Itself From Terrorism

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US Supports Pakistan's Right To Defend Itself From Terrorism

US declare Pakistan right to self-defense against scourge of terrorism

After Economy Minister Rana Sanaullah threatened to strike Tehreek-e-Taliban Pakistan (TTP) strongholds within Afghanistan if action against them was not done, the US support Pakistan to secure itself from terrorism.

As claimed by the foreign minister in a conversation with a Pakistani TV channel,

“Islamabad may strike the TTP in Afghanistan if Kabul doesn’t quite take steps to evacuate them”

The National Security Committee (NSC), led by Prime Minister Shehbaz Sharif, also determined on Monday that no entity will be authorized to offer sanctuary and assist terrorists, and Pakistan retains all privileges to defend its citizens.

Since the Tehreek-e-Taliban Pakistan (TTP), an illegal entity, broke its November armistice with the government, there has been an increase in terrorist activity in Pakistan, notably over the past several months.

Ned Price, a spokesman for the US State Department, responded to Pakistan’s pledge against terrorism by saying that his nation is very well aware of the NSC statement.

 Terrorism

“Terrorist assaults have caused great anguish for the people of Pakistan”

Pakistan is entitled to self-defense against terrorists Price stated during a weekly Washington press conference.

As per him, the US calls on the Taliban to keep their word to ensure that Afghan soil is never once again exploited as a staging point for global terrorist assaults.

The spokesman observed,

“These are some of the very obligations that the Taliban have been unable or unwilling to fulfill to date”

“The Taliban have pledged loyalty to the world community. However, what is more, essential is that they have committed to the Afghan people. These are the obligations that matter most to us. A concentration on human rights is one of the assurances the Taliban have made but have often violated when it pertains to their own people “He was agitate.

The spokesperson for the State Department stated, “We will act in a way that both demonstrates our categorical condemnation and preserves our support for the Afghan people as long as the Taliban is unable to uphold these obligations. And we’ll take enormous care to avoid doing anything that would put the Afghan people’s humanitarian sovereignty in even more jeopardy.”

33 Contestants Were Expired While Municipal Elections

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33 Contestants Were Expired While Municipal Elections

Delayed municipal elections in 45 areas due to unfortunates deaths.

Elections in 45 municipalities will take place at a subsequent time as a consequence of the periodic delays and cancellations of the second phase of the municipal elections in Hyderabad and Karachi. 33 contestants who had filed their certificate of candidacy the previous year have unfortunately passed away.

In the meanwhile, 704 of the 19,867 candidates in the race for multiple positions have been nominated unanimously to preside as chairperson, vice chairmen, and general members of union councils, town councils, and district councils in sub-districts of the Karachi and Hyderabad legislative zones.

As per data from the Election Commission of Pakistan (ECP), half of the 16 contestants who perished from the Karachi Division had submitted their candidacy for the chairman and vice chairman positions, and the other eight were contesting for general member vacancies.

Consonance:

In accordance with the official data, one general member contender perished in the district of Malir, one vice chairman candidate, one chairman candidate, and one general member contender each died in the district of Korangi, and two general member contestants died in the district of East.

Additionally, one chairman candidacy and four general member candidates perished in District Keamari, while four vice chairman candidates and one chairman nominee perished in the Central and West districts. In the Hyderabad Division, seventeen further hopefuls perished.

During the general election in Pakistan, a woman casts her vote at a voting station.

33 Contestants Were Expired While Municipal Elections

The ECP had assured the Sindh government that the second round of the LG elections will take place in Karachi and Hyderabad on July 24, 2022, but it later postponed those elections due to torrential rainfall and ensuing flooding in those cities.

The regional government petitioned their deferral for three months after the ECP adjourned the elections for October 23 on October 18. Because the regional government had dispatched police in the wetlands, it was unable to provide the polling places with the necessary level of protection.

The Pakistan Tehreek-e-Insaf and the Jamaat-e-Islami petitioned the Sindh High Court after the setbacks started happening, and on November 15 it compelled the ECP to publish the date of the LG elections within 15 days. The ECP revealed the amended date of January 15 on November 22.

As per the official results, five general member aspirants and one chairman candidate won in the Malir, East, and Keamari districts of Karachi, while the rest of the candidates won a variety of seats in the nine districts of Hyderabad, including general member, town councilor, and district member.

Govt Set Timings for the Closure of Markets, Cafes, and Wedding Halls

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Govt Set Timings for the Closure of Markets, Cafes, and Wedding Halls

Govt mandate close by 8:30 PM, weds by 10:00 PM, aiming to save Rs 62B

At a press conference today, Defense Minister Khawaja Muhammad Asif made the announcement. Govt offices are no longer permitted to purchase inefficient electrical equipment. He also made several cost-cutting announcements since the nation’s economy remains fragile

Prime Minister Shehbaz Sharif gave the order to reduce electricity use in federal government offices by 30% and forgo any superfluous electricity use during the federal cabinet meeting earlier today.

Government offices are no longer permitted to purchase inefficient electrical equipment. Beginning on July 1, 2023, the production of inefficient electric fans will be prohibited.

A new tax will be levied starting on July 1 on the production of inefficient electric fans. Annual savings of Rs. 15 billion are anticipated.

Beginning on February 1, 2023, incandescent bulb production will be prohibited. The manufacture of incandescent bulbs will be subject to an extra duty as of February 1. 22 billion rupees are anticipated to be saved yearly.

The federal government must install conventional baffles in geysers within a year. 92 billion rupees should be saved as a result.

To save Rs. 4 billion yearly, the Federal Govt has also ordered that alternate street lights be turned on at night.

Additionally, the federal government has mandated hastened e-bike introduction. Fuel bikes consume $3 billion in gasoline annually. The introduction of e-bikes will eventually phase out fuel bikes.

A comprehensive awareness campaign has also been established by the federal government to encourage people to adopt austerity measures.

PEMRA will see to it that during the previously allotted 10% of their advertising time, TV and radio networks air advertisements regarding this awareness campaign.

After gaining clearance from PM Shehbaz, the federal Govt would notify the work-from-home (WFH) policy for public sector employees in the following 8–10 days.

The FBR has been urged by the federal Govt to issue a separate tax directory of the lawmakers. It will make it possible for citizens to learn how much tax their elected officials truly pay.

 

 

90-Years-Old Pak-Hind Wedding Card Gone Viral

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90-Years-Old Pak-Hind Wedding Card Gone Viral

The wedding invitations have evolved from old to modern in 90 years.

The 90-years-old Urdu invitation was scrawled and shared on Twitter by Karachi-based fashion designer Sonya Battla in a photo. It was created in 1933 for the Delhi wedding of her grandparents. Since it was tweeted on December 30, the image of the straightforward invitation has received over 9,000 likes and hundreds of retweets.

Besides this, a 90-years-old viral wedding card written in Urdu that was just released by Twitter user Sonia Batla from Karachi when penning her grandfather’s 90-years-old wedding invitation is presently being discussed on social media.

Sonia declared in a tweet that the wedding card for her grandparents was written in Delhi the year of the wedding, 1933.

As stated by a Twitter user who translated this 90-years-old invitation, Muhammad Ibrahim wrote it for his son Hafiz Muhammad Yousaf’s wedding, which was set for April 23, 1933.

Ibrahim recommends that guests meet at his residence on Qasim Jan Street in Delhi so that they can proceed with the family to the bride’s home in Kishan Ganj. The translation states that the baraat, or the groom’s wedding party, was scheduled to depart at 11 am. Ibrahim adds a veiled appeal for his guests to be on time before signing off on the letter, stating, “Your punctuality will make me comfortable.”

For the nuptials of his son Hafiz Muhammad Yusuf, which were slated for April 23, 1933, Niazmand Ibrahim invited the guests to Gali Qasim Jan during the wedding feast. A Valima has also extended an invitation to him for April 24, 1933.

Many individuals who commented on Battla’s tweet mentioned that the groom’s home is close to that of renowned poet Mirza Ghalib. A Twitter user echoed this by writing, “Your ancestors were Mirza Ghalib’s neighbors:) Gali Qasim Jan. Mohalla was unique, though.

Pakistan Reports the First Case of Most Infectious Omicron Variant

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Pakistan Reports the First Case of Most Infectious Omicron Variant

NIH and AKU confirmed a highly infectious Omicron strain subvariant.

XBB, one of the three strains of the Omicron variety wreaking havoc in China, has reportedly been discovered in Pakistan, according to reports from the NIH and AKU.

The reports claimed that NIH routinely performs genome sequencing on Coronavirus samples, citing a senior NIH official.

Due to Pakistan’s low rate of coronavirus positive, however, there are only a few samples available for sequencing.

The representative clarified that the nation is not currently at imminent risk of a fresh Coronavirus wave. However, NIH constantly keeps an eye on the situation and is ready for anything.

Separately, AKU officials claimed that Pakistan has not yet discovered the other two strains, including the most hazardous BF.7 subvariant of the Omicron variant, dominant in China.

However, Dr Faisal Mehmood of AKU issued a warning that BF.7 might be spreading throughout the nation. Pakistanis have, however, grown more resistant to the Coronavirus than Chinese people because of a combination of immunisations.

Due to the lack of travel restrictions intended to stop the spread of BF.7 into Pakistan, Dr Faisal Sultan, a former SAPM on health, has asserted that Pakistan may already be infected.

The BF.7 strain has not spread to Pakistan, according to Prof. Saeed Khan, leading molecular scientist and professor of pathology at Karachi’s Dow University of Health Sciences (DUHS).

There would have been a noticeable increase in Coronavirus cases if it had been found in the nation.

He continued by saying that BF.7 is highly contagious, innate and acquired immunity are easily overcome. Up to 20 individuals can contract the BF.7 virus from a single infected host.

Punjab Might Experience The 7th Wave Of Coronavirus

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 Punjab Might Experience The 7th Wave Of Coronavirus

Punjab health experts suggest winter booster doses enhanced COVID-19.

They are worried since the majority of people of Punjab are now vulnerable to the new variety known as “BQ-1,” a sub-variant of the Omicron, due to a significant portion of the population receiving booster injections five months ago.

The decisions were made at a meeting held on Monday by Punjab’s directorate of health services. In order to combat the virus’ seventh wave, the committee decided to give the Communicable Disease Control (CDC) of the most recent Omicron subvariant to Punjab a significant role.

An official stated that a World Health Organization (WHO) representative warned the group of the potential risk of the 7th wave of Covid-19 reappearing in Punjab.

He mentioned the high transmissibility of the new sub-variant of Omicron BQ-1 and claimed that this had caused an undesirable scenario in China due to the hundreds of thousands of brand-new cases in the nation.

The responses confirmed that the new sub-variant of the Omicron required immediate action by establishing all existing programs to avoid its spread in Punjab based on the official’s assertion.

To prepare for the anticipated seventh wave of the virus, it has also been proposed that an emergency session of the technical workgroup be held today (Tuesday).

To better monitor and sequence cases, genomic sequences, field investigations, laboratory assessments, and other data, the authorities should take the necessary steps.

 “The Legend of Maula Jatt” In Pakistan Exceeds The $1 Billion Mark

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 "The Legend of Maula Jatt" In Pakistan Exceeds The $1 Billion Mark

The star-studded movie The Legend Of Maula Jatt remains on a roll to a notch higher, earning Rs. 1 billion internationally at the box office.

The Legend of Maula Jatt, the most well-known and highest-grossing movie in Lollywood, has broken yet another record, this time laying a benchmark for box office success for films to be released in theaters.

On Sunday, the film’s official Instagram account published a poster with the description, “On the final day of 2022, the film surpassed the astonishing milestone of 100 crores [Rs1 billion] in Pakistan.”

A never-before-seen photo from the set of the movie that director Bilal Lashari uploaded was captioned, “Perfect timing as  Maula Jatt crosses 100 crores tonight at the Pakistani box office and $10 million USD internationally. Once more, I want to express my gratitude to the members of team MJ and the millions of people who have seen The Maula Jatt and found it to be fantastic.

In The Legend of Maula Jatt, Punjab’s own superhero is reimagined for a global audience as a reworking of the 1979 cult movie Maula Jatt. Fawad Khan, Mahira Khan, Humaima Malick, Gohar Rasheed, Faris Shafi, Ali Azmat, Raheela Agha, Babar Ali, Saima Baloch, Shafqat Cheema, Nayyar Ejaz, and Resham are among the actors who appear in the movie.

BBC Urdu Radio News Disclosures Ceased After Over 20 Years

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BBC Urdu's Radio News Disclosures Ceased After Over 20 Years

BBC Urdu discontinue radio news update to Pakistan after over 20 year.

On Saturday night, the broadcast of the BBC Urdu service’s final radio newscast officially ended the service.

According to Asif Farooqi, editor of the BBC Urdu service, BBC broadcasts won’t be available on the radio any longer, but that does not imply the broadcaster is losing its “relationship with audio.”

The BBC Urdu website showed a video of Farooqi saying, “The Urdu service is entering a new era…

This infrastructure will still be present, and we’ll use it to give you audio in a digital format

In the film, several BBC staffers are shown discussing similar briefings and their termination.

Mehwish Hussain, a member of the BBC Urdu service staff, claimed that FM bulletins and her job with the Pakistan regional service started around the same time.

“When we began publishing these bulletins in 2004, it was a tremendously exciting event. It was such an innovative and well-received product that it gained popularity rapidly, she said.

“I have a great sense of pride in having been a part of launching the bulletins”

Saad Sohail, a different BBC employee, asserted that they were conscious of their obligations each time they took the stage for these programs.

In addition, Sohail said, “This journey was more significant because when people wrote letters to us from Balochistan and other far-flung areas and said they could acknowledge our voice, one feels that joy that we were able to spread information that they could not have discovered through the mainstream media.”

According to Farooqi, the broadcaster was developing a strategy for the impending release of podcasts and audio stories.